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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd351007e745be3ff5e9a7747cdee8fc864ee4dc08205bfe27e6be5b03fc8d4f' 
  AND token = 'oqRgT++HV1K6BN8/jwIcMRbl9//Sts2yEZcymY/x+JI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}