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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c9818ca087093e28fb5fb22b2d72227cb1be11c78ee71385ca1da7580e1837a' 
  AND token = 'VaNoYxy/KKg0WXAgJ6UF0I4/xf8/9WZP/uM8ot+uJhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}