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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f09d486f997b2b2cead9c396ad0104c635b00f00888c2f3dc0f81bc1d5eefd7c' 
  AND token = 'VamvZdpoaIe9Hrh8JtKN1rou6/ZNYU7j2AF3J5U4lyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}