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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2132ce6613551ba6879925cc148f32494f1857af8b772085a6fe531fe127f3d3' 
  AND token = 'yGp0ESL0L+VzSMIAz13hxeeM22RUny/zj1IbhIfAI1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}