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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c04c8122389e2e68ce91402331ee17c8bfd51c8e4a3817956233e266224f191' 
  AND token = '6k2V3TB9CpyFhSbchxfPKDv7iolv9a2bTBTMc6ymxYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}