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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97e1c474ac5ba0ab67671c64da5aa7b10eb45faa17400bb8f4ca6e1650e57f52' 
  AND token = 'pMZyyfId0JOiYi2p5HR0EbWEWSJkmV/YD+oMmkrAIzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}