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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4fda9393d48b510f4bd2cf4e6eee28b0a008361018e6acc5559326f4439fb28' 
  AND token = 'eMJx4TaTlPSDcFH5D9u9Y1x+JVikFNUpqYmS3OA6QlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}