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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b549004a1a33c2cc7eff01237b94e0b1fd7bdc328baa8da1e5e76c4a0bdd967c' 
  AND token = 'pXPS42ipGhAHUwye+7KWgRu24y+EQkzrOdOkTXAhVw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}