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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241a6d75d5b56fee10663c7b7b2b48daec17ebcc4a029d4bb382908d7842f5d6' 
  AND token = 'Jg6K5OIPo/cFIbrjY2qHJLcY+9Y+SXmI7/1+pM96m8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}