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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3475f3ead46197795e161d3c2abe6a8bd60d16667cd767d5dcb7311f04812866' 
  AND token = 'LXspNYu8E8RAfpA/gylYG4SNEAcIIVSz3OAzbEDJaUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}