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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '472373bb6f61f447e9fdc4710c04a7d624246a8a0ac5312e04d6dc509c86d77a' 
  AND token = '+UkaqC885GqFbzwRVwTTHg4c4zBamzKsSTUNXrGLm7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}