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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb48e3b12fb5744b20d2b05ebe1b10875bd3ab778444efe934747987a1ccb3bb' 
  AND token = '1k8Yy9wlk7MfErzJkVGfPTkcamCB532/S63Vj1O4aY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}