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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ffca8a17e882ca494accfa6f9a7d4ce66895a7b42cd8a9f260bdd75d2bb9521' 
  AND token = 'NKaXVx/gJ78B08f1xmVn3NZtBBvMoL2nihTbwWubglw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}