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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45d92ebfb64a1003756f2ef37c67ec1ec664a6a66c64d4c582fb57a0282f837' 
  AND token = 'oJJFHk4Xm3Y9HItZK8f6GYF0ybsoq1xDjL+DlKWLCRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}