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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68a4aef9e62b1fa97d7aa155fc079b4295c967831b28c9f2748dead7003171b3' 
  AND token = 'PhCOo/aN3UlbGNvXaKEUL6pka6FPYIdNaUFTG75MYhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}