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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fe57b23e7751c404f0e80413f1a90cee7fd3c9031168f4484eed0df9fe79b27' 
  AND token = 'XXBVlUBSJQaHzhYf8YBxc6s8IIDT+TMUlRwGL39AU0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}