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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f770800d3c543135177c7d17ad3f87fa56c0f0e7926765a86e33b218ad7d706f' 
  AND token = 'PHsHw5fBQSYHcFkCO9qtVhpwmB8tNlTsktvxVMbXiHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}