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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c45bcbc12515272277518aadd80dd1ebf298a68f689990b94dcf91f3c25d58' 
  AND token = '8dF7eiS2MbLfabW1zSCFOvz5BTTF+J2rTA8YHWOyO48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}