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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '496f678eb1d4099704129550c968224d96ecab3292bbdafa2af4e37e664a9040' 
  AND token = 'ufok6dzTViJeDHVoLU8XGpnbZZCt4UvmWQK5OF6p9GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}