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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e759571ba66d19ca46c79ca945c396182226e67a87d04ac9ca825928f2918d' 
  AND token = 'tN2P9yB5bP+XaY8Q+XaAVp2/AmUJiRVW6LfKfVTVQls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}