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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '336b393f7eb0626dd93eecd3fa1965a66f1c4da8e642536819996001873eff40' 
  AND token = 'BJ8cYfT9LbJv9VH6E2+3xdz1tgNRb2bYn8/l5aRraZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}