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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1425f6aa32d6ec9f3d332b2563449f10dc17d71cf55a104200536f7b25f9e55f' 
  AND token = 'x/EkSKLRX1r7V2Vp+x2oFqkbUMwI3ICxQ2LwT8msUVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}