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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f84d87d7fc444b499b43396fd9fcb5ff2a6c9f040f114f0581a4415b123a7d70' 
  AND token = 'VVVADkxmyQQ/cD1pz5KCFSg4tAZ79FAFkdFq9zm3v3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}