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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74780dd53c6ceef5580411c852a06b716a2d25645417dac2b0e188e0eeacf94f' 
  AND token = 'N0L6N+xV3nsOkFoSKPntO2tEg1Ovd1qFHECcSRNc/rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}