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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd910d8ce9f0194848c8a45fa08f5a84d27022e939d42c5416976325820f7094d' 
  AND token = 'lLuM1WF4l4iqW00VkFDGhsNVvF+nTJbQic3/dp1xvZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}