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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7404543e2173ba6caafb272fd4cb7a080596cf9db7c9a5b2dc5a7e8af0aa56e' 
  AND token = 'YEkIeZ/T7m2RndgXQJ+JtsmqvIVB86D1sL3iJiXL3Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}