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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ba3168879be5ed9bbaad37e0a8bff61b4fe1d3a250cd31eb34b05105357de97' 
  AND token = 'bHM3yu0+zm11nkPydxJ8X8Cvwvg+emZ9StUAtcmAn4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}