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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724c24fb027518b7f9e9f9cc079d516e7353940131defaaf6372c08ff6eff182' 
  AND token = '8TWFJJ1ulGO2nG5QxHmY1ZxSggUiOPlo5J0pUvFg1Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}