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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0926be91eeee2408925caf650be1c14bd1d9a195d15249e34a1e4ea43b14bf8' 
  AND token = '+PV/lQPTDgR40de3cKryRNP0APbSUep9PhzOOKBi/aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}