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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3392588531983e9d5465842b9440b1a8eb014442e425f5e4701a09b36f6220b2' 
  AND token = 'UzCbR4+MDl1Slky7fAGKiDWws6BAULqt1QZA1X/h+sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}