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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ce22ae382ff35543a87745faca96d7a13b25366f6e6a8f6d655ccb9bb0379a' 
  AND token = 'rcTpy0G9Y0Oqo+ZpsLivaOmRglP65WA+TBslXUbAivs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}