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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09354ffb8dcd4848bc451a4bda98b66af086846b20f51a3c874e5d1cecf2d688' 
  AND token = 'Syo+JkQSgayfV+Td/sTHrqtkWOjMGU9cz3w3Oq7ZC70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}