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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad4ce45862a1114435c1440593c4d88d29ef1fa33bd9bb6d4cc1058003149492' 
  AND token = '37yRibWX2LP7eqeTrR+cjOzdnTsyZFmCoBl07Xiq8W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}