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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad689dd373ecbfec3a80c51675ec99f34ca34a5bc999ec7da7bf3a54f42e3643' 
  AND token = 'HDY18/rYDm8LFEZvzfkyih/VLO/0nK9nfQGXw91DsDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}