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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f114b4ea1544667c56617b2188253d2d526fd16b99d6b2f4b554699db1d268' 
  AND token = 'zlgg3PPyIj+nF95Lvp1OR7699VrtohSzQNh+6Y2ICzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}