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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7c816e9e7c8a4854d3946b49251a73129493479fd5bfc6efa0af341e394ee05' 
  AND token = '+Jg6GIXd3zIj0gLQRpePldEix7aCBYzedVv6Ol4oI5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}