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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1621da170ecba3711f0638f0354d54197944b942b5e6888b892520fa755e43' 
  AND token = 'M5tvOEqVcHy5tNgX7pTXCtKA2c3SBF0ek5yr7laY9ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}