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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c4672d3daa1f2a8993dfe80922dda656cac326468411e99dacb5297e6a72c6' 
  AND token = 'GetN+o1jzN4phbP7PRuPq6GVNqQ0ca0Oqvj4tx/qQ8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}