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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8a80c07e5fad9952f5284eadac5be1704148ded3503398d94d7e6724fbf3ef' 
  AND token = '7uz4egD8X0O7o/TOCWKp0c+SAtXuko+T8AFIXWWgu0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}