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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35cf1d6d7207678c299557e7db57634836e2932c2adb7e09e3dfdf2c35461b62' 
  AND token = '39fQwLFM+IZQkjzolDpUHtn5NDe4YoK0CoO2cMlTvbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}