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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad80d681d01d1405f20ff2fd1e2bd040880c18da431dd30772ee6f7c6aa56263' 
  AND token = '/C6hBHPbh3W5Y3T+wY/1egisotX6um24FA2XL3pTwJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}