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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56145fc1e8dd96afb6d782a416afbfe7652a2b339f87258983ee0fe0444bd46f' 
  AND token = 'eTjsxx8v2TKSV7SkXUMIN+u50SCA7NKeFlIFOIEXk6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}