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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6b0f0c35b0fa052ca660057fc49a4c56c782bad2c7b7abb1b6328da10ab34e' 
  AND token = 'zJQou6czDUM/s4j8fZTpi7i7pG2qu+YS+NGrg+G7nOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}