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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1ccd2ea97e5f9a0bbff633b9f2ea77f3aed4ed04d330d40f839c0125d746a3' 
  AND token = '17AFS2eqAC62nN1zNamJUyG/xgRaY8PivIgoxBHQ3bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}