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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141b7335749f36b59d20f1c20dbe9f25fc9ff7559cd31fd727b5fb4b92e6bb2b' 
  AND token = '4P3zM0BpWMUlsk9+A5jLf8e9tH+XsQiMbFS/0P1qGTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}