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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d7cad4881122dd4d2887c25d38a114298f844f14c210ebd0efd5b4def97bb0' 
  AND token = 'p3i33zWBeAKjCBnA0Y7tX2SK8+MTFMuE1XpR0DkKhxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}