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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a2ba413d03ac7afb5e32388b552b9375c37742c54b2c220ec4239e189d4ddfc' 
  AND token = '0GHBxNpCoudj6dmx787nptpwtVp+IT30Ee9T24fqki0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}