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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28da9d634cb8f17cf6604e11b1a9ed38045a7c50b10fe3d114750c8664cf9305' 
  AND token = 'HK+fbwjWJIzx936hI8bWW/1LQSUDnhQImDr4Lnij4LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}