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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc7789291934b343449c540ea727ef8285a27bfd0d3572e4fc3657abd6bd5b31' 
  AND token = 'OzC3Kf0Se4fYXmadALfbiCIJVMzR66Vk///SjYzX6kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}