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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5eed34da21b11314d1be8178708131ac2dfdaf628b20fe4c046a102382b3165' 
  AND token = 'A327/MrBwdNjVfB1TVnCH0lSvdA2GXMi2ftHZWXGuWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}